By Dr. Marie Sénant
Multiple Sclerosis (MS) is an inflammatory autoimmune disease of the central nervous system, with a diagnosis based on a combination of clinical, radiological, and biological criteria.
The Kappa Index, a quantitative marker of intrathecal synthesis of kappa light chains, is now emerging as a complementary tool to the detection of oligoclonal bands.
We invite you to revisit the pathophysiological foundations of MS, explain the current diagnostic criteria, and highlight the contribution of the Kappa Index in the biological diagnostic strategy.