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Hematology at the heart of Cerba expertise

Hematology holds a prominent place in Cerba's historical expertise; and encompassing various fields: immunohematology, hemostasis and red blood cell pathologies

background

Immunohematology

This plays a crucial role in preventing transfusion accidents and monitoring fetal-maternal incompatibilities in order to avoid Hemolytic Disease of the Newborn (HDN).
We carry out a full range of analyses in this sector, including:

  • Blood grouping
  • Screening and identification of anti-erythrocyte antibodies
  • Antibody titration and microtitering in pregnant women
  • Direct antiglobulin test

We work closely with the National Reference Centre in Perinatal Hemobiology (CNRHP) to monitor allo-immunized patients (quantitation).
 

Go to the Hematology catalog

Hemostasis

This field, which deals with coagulation disorders, enables early and accurate diagnosis, leading to optimal patient care.

Biological expertise and a wide variety of specialized tests are available:

-Diagnosis of hemorrhagic diseases: with tests for coagulation factors, Willebrand factor, study of fibrinolysis, and detection of anti-factor antibodies.

-Diagnosis of constitutional and acquired thrombophilias: including tests for physiological inhibitors (antithrombin, proteins C and S), activated protein C resistance, lupus-type circulating anticoagulants, as well as genetic testing for factor V Leiden and prothrombin gene mutations.

-Monitoring anticoagulant treatments: heparins (UFH and LMWH), VKAs, as well as direct oral anticoagulants (DAAs).

-Diagnosis and follow-up of Thrombotic Thrombocytopenic Purpura (TTP): ADAMTS 13 and anti-ADAMTS 13 autoantibodies

 

The laboratory uses a variety of methods, including chronometric, chromogenic, immunological and molecular biology techniques, to ensure reliable, high-precision results.

Red blood cell pathologies

Red blood cell pathologies represented by hemoglobinopathies such as sickle cell disease or thalassemias, but also enzyme deficiencies (G6PD, pyruvate kinase...). 

Two techniques are used to diagnose hemoglobinopathies: Capillary electrophoresis and high-performance liquid chromatography (HPLC). This approach enables identification of the main hemoglobin variants (S, C and E).

Highly qualified biologists

Expertise provided by four biologists specialized in hematology, who are able to carry out all the tests and are in daily contact with clinicians.

Hematology medical team